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Protein-Directed Dynamic Combinatorial Chemistry: An Efficient Strategy in Drug Design

[Image: see text] Protein-directed dynamic combinatorial chemistry (P-D DCC) is considered a powerful strategy to identify ligands to pharmacologically relevant protein targets. The protein selects its affinity ligands in situ through a thermodynamic templated effect in which the library composition...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Canal-Martín, Andrea, Pérez-Fernández, Ruth
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581073/
https://ncbi.nlm.nih.gov/pubmed/33110958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03800
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