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Protein-Directed Dynamic Combinatorial Chemistry: An Efficient Strategy in Drug Design
[Image: see text] Protein-directed dynamic combinatorial chemistry (P-D DCC) is considered a powerful strategy to identify ligands to pharmacologically relevant protein targets. The protein selects its affinity ligands in situ through a thermodynamic templated effect in which the library composition...
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| Published in: | ACS Omega |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Chemical Society
2020
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7581073/ https://ncbi.nlm.nih.gov/pubmed/33110958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03800 |
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