Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis

The liver is a central regulator of metabolic homeostasis and serum metabolite levels. Hepatocytes are the functional units of the liver parenchyma and not only responsible for turnover of biomolecules but also act as central immune signaling platforms. Hepatotropic viruses infect liver tissue, resu...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Lercher, Alexander, Popa, Alexandra M., Viczenczova, Csilla, Kosack, Lindsay, Klavins, Kristaps, Agerer, Benedikt, Opitz, Christiane A., Lanz, Tobias V., Platten, Michael, Bergthaler, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580883/
https://ncbi.nlm.nih.gov/pubmed/33045014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008973
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