Reproducible Antigen Recognition by the Type I-F CRISPR-Cas System

CRISPR-associated proteins 1 and 2 (Cas1–2) are necessary and sufficient for new spacer acquisition in some CRISPR-Cas systems (e.g., type I-E), but adaptation in other systems (e.g., type II-A) involves the crRNA-guided surveillance complex. Here we show that the type I-F Cas1–2/3 proteins are nece...

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Bibliografiske detaljer
Udgivet i:CRISPR J
Main Authors: Wiegand, Tanner, Semenova, Ekaterina, Shiriaeva, Anna, Fedorov, Ivan, Datsenko, Kirill, Severinov, Konstantin, Wiedenheft, Blake
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580607/
https://ncbi.nlm.nih.gov/pubmed/33095052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2020.0069
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