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Protocol for Immuno-Enrichment of FLAG-Tagged Protein Complexes

This protocol describes immunoprecipitation of proteins associated with FLAG-tagged recombinant proteins followed by mass spectrometry-based proteomics to identify the associated interactome components. FLAG epitope was chosen, because existing high-affinity monoclonal antibodies allow for sensitive...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Valdez-Sinon, Arielle Nicole, Gokhale, Avanti, Faundez, Victor, Bassell, Gary Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580096/
https://ncbi.nlm.nih.gov/pubmed/33111116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100083
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