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Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography

The dynamic nature of cellular machineries is frequently built on transient and/or weak protein associations. These low affinity interactions preclude stringent methods for the isolation and identification of protein networks around a protein of interest. The use of chemical crosslinkers allows the...

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Detalhes bibliográficos
Main Authors: Zlatic, Stephanie A., Ryder, Pearl V., Salazar, Gloria, Faundez, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925877/
https://ncbi.nlm.nih.gov/pubmed/20216526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1855
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