Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway

BACKGROUND: Chemotherapy is currently one of the most effective treatments for advanced breast cancer. Anti-microtubule agents, including taxanes, eribulin and vinca-alkaloids are one of the primary major anti-breast cancer chemotherapies; however, chemoresistance remains a problem that is difficult...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Lai, Tsung-Ching, Fang, Chih-Yeu, Jan, Yi-Hua, Hsieh, Hsiao-Ling, Yang, Yi-Fang, Liu, Chun-Yu, Chang, Peter Mu-Hsin, Hsiao, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579951/
https://ncbi.nlm.nih.gov/pubmed/33087151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00600-2
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