Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity of urothelial carcinoma cell lines via the NF-κB pathway

The high mobility group box 1 (HMGB1), which is a highly conserved and evolutionarily non-histone nuclear protein, has been shown to associate with a variety of biological important processes, such as transcription, DNA repair, differentiation, and extracellular signalling. High HMGB1 expression has...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Zhichao, Zhong, Zhaohui, Zhang, Lei, Wang, Xinjun, Xu, Ran, Zhu, Liang, Wang, Zijian, Hu, Shanbiao, Zhao, Xiaokun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523846/
https://ncbi.nlm.nih.gov/pubmed/26239046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12807
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