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In vivo vaccination with cell line-derived whole tumor lysates: neoantigen quality, not quantity matters
BACKGROUND: Cancer vaccines provide a complex source of neoantigens. Still, increasing evidence reveals that the neoantigen quality rather than the quantity is predictive for treatment outcome. METHODS: Using the preclinical Mlh1(−/−) tumor model, we performed a side-by side comparison of two autolo...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7579816/ https://ncbi.nlm.nih.gov/pubmed/33087163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02570-y |
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