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Cyclin-dependent kinase inhibitors in head and neck cancer and glioblastoma—backbone or add-on in immune-oncology?

Cyclin-dependent kinases (CDK) control the cell cycle and play a crucial role in oncogenesis. Pharmacologic inhibition of CDK has contributed to the recent clinical approval of dual CDK4/6 inhibitors for the treatment of breast and small cell lung cancer. While the anticancer cell effects of CDK inh...

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Библиографические подробности
Опубликовано в: :Cancer Metastasis Rev
Главные авторы: Riess, Christin, Irmscher, Nina, Salewski, Inken, Strüder, Daniel, Classen, Carl-Friedrich, Große-Thie, Christina, Junghanss, Christian, Maletzki, Claudia
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897202/
https://ncbi.nlm.nih.gov/pubmed/33161487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09940-4
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