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The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression

Multiple mechanisms contribute to the survival and growth of metastatic castration‐resistant prostate cancer (mCRPC) cells without androgen, including androgen receptor splice variants (AR‐V) and de novo intratumoral androgen synthesis. AKR1C3 is a critical androgenic enzyme that plays different rol...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Bin, Wu, Shiqi, Fang, Yong, Sun, Guangxi, He, Dalin, Hsieh, Jer‐Tsong, Wang, Xinyang, Zeng, Hao, Wu, Kaijie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7579719/
https://ncbi.nlm.nih.gov/pubmed/32902124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15831
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