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The AKR1C3/AR‐V7 complex maintains CRPC tumour growth by repressing B4GALT1 expression
Multiple mechanisms contribute to the survival and growth of metastatic castration‐resistant prostate cancer (mCRPC) cells without androgen, including androgen receptor splice variants (AR‐V) and de novo intratumoral androgen synthesis. AKR1C3 is a critical androgenic enzyme that plays different rol...
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| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7579719/ https://ncbi.nlm.nih.gov/pubmed/32902124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15831 |
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