Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival

Prostate cancer (PCa) is the most common malignancy and is the second leading cause of cancer among men globally. Using a kinome‐wide lentiviral small‐hairpin RNA (shRNA) library screen, we identified phosphoinositide‐dependent kinase‐1 (PDPK1) as a potential mediator of cell survival in PCa cells....

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Nalairndran, Geetha, Hassan Abdul Razack, Azad, Mai, Chun‐Wai, Fei‐Lei Chung, Felicia, Chan, Kok‐Keong, Hii, Ling‐Wei, Lim, Wei‐Meng, Chung, Ivy, Leong, Chee‐Onn
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578863/
https://ncbi.nlm.nih.gov/pubmed/32926495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15876
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