Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45(–) TER119(–)Erythroid and Lymphoid Progenitors

p32/C1qbp regulates mitochondrial protein synthesis and is essential for oxidative phosphorylation in mitochondria. Although dysfunction of p32/C1qbp impairs fetal development and immune responses, its role in hematopoietic differentiation remains unclear. Here, we found that mitochondrial dysfuncti...

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Veröffentlicht in:iScience
Hauptverfasser: Gotoh, Kazuhito, Kunisaki, Yuya, Mizuguchi, Soichi, Setoyama, Daiki, Hosokawa, Kentaro, Yao, Hisayuki, Nakashima, Yuya, Yagi, Mikako, Uchiumi, Takeshi, Semba, Yuichiro, Nogami, Jumpei, Akashi, Koichi, Arai, Fumio, Kang, Dongchon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578749/
https://ncbi.nlm.nih.gov/pubmed/33103089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101654
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