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Hit-to-lead optimization of novel benzimidazole phenylacetamides as broad spectrum trypanosomacides
Trypanosoma cruzi and Trypanosoma brucei are the parasitic causative agents of Chagas disease and human African trypanosomiasis (HAT), respectively. The drugs currently used to treat these diseases are not efficacious against all stages and/or parasite sub-species, often displaying side effects. Her...
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| Publicat a: | RSC Med Chem |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7578707/ https://ncbi.nlm.nih.gov/pubmed/33479668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00058b |
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