Loss of the seipin gene perturbs eggshell formation in Caenorhabditis elegans

Seipin, an evolutionary conserved protein, plays pivotal roles during lipid droplet (LD) biogenesis and is associated with various human diseases with unclear mechanisms. Here, we analyzed Caenorhabditis elegans mutants deleted of the sole SEIPIN gene, seip-1. Homozygous seip-1 mutants displayed pen...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Bai, Xiaofei, Huang, Leng-Jie, Chen, Sheng-Wen, Nebenfuehr, Benjamin, Wysolmerski, Brian, Wu, Jui-Ching, Olson, Sara K., Golden, Andy, Wang, Chao-Wen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578359/
https://ncbi.nlm.nih.gov/pubmed/32820022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192997
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