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Loss of the seipin gene perturbs eggshell formation in Caenorhabditis elegans

Seipin, an evolutionary conserved protein, plays pivotal roles during lipid droplet (LD) biogenesis and is associated with various human diseases with unclear mechanisms. Here, we analyzed Caenorhabditis elegans mutants deleted of the sole SEIPIN gene, seip-1. Homozygous seip-1 mutants displayed pen...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Bai, Xiaofei, Huang, Leng-Jie, Chen, Sheng-Wen, Nebenfuehr, Benjamin, Wysolmerski, Brian, Wu, Jui-Ching, Olson, Sara K., Golden, Andy, Wang, Chao-Wen
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578359/
https://ncbi.nlm.nih.gov/pubmed/32820022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192997
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