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Loss of the seipin gene perturbs eggshell formation in Caenorhabditis elegans

Seipin, an evolutionary conserved protein, plays pivotal roles during lipid droplet (LD) biogenesis and is associated with various human diseases with unclear mechanisms. Here, we analyzed Caenorhabditis elegans mutants deleted of the sole SEIPIN gene, seip-1. Homozygous seip-1 mutants displayed pen...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Bai, Xiaofei, Huang, Leng-Jie, Chen, Sheng-Wen, Nebenfuehr, Benjamin, Wysolmerski, Brian, Wu, Jui-Ching, Olson, Sara K., Golden, Andy, Wang, Chao-Wen
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7578359/
https://ncbi.nlm.nih.gov/pubmed/32820022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192997
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