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Real-time compaction of nanoconfined DNA by an intrinsically disordered macromolecular counterion
We demonstrate how a recently developed nanofluidic device can be used to study protein-induced compaction of genome-length DNA freely suspended in solution. The protein we use in this study is the hepatitis C virus core protein (HCVcp), which is a positively charged, intrinsically disordered protei...
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| Udgivet i: | Biochem Biophys Res Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577930/ https://ncbi.nlm.nih.gov/pubmed/32951838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.06.051 |
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