Llwytho...

Real-time compaction of nanoconfined DNA by an intrinsically disordered macromolecular counterion

We demonstrate how a recently developed nanofluidic device can be used to study protein-induced compaction of genome-length DNA freely suspended in solution. The protein we use in this study is the hepatitis C virus core protein (HCVcp), which is a positively charged, intrinsically disordered protei...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Biophys Res Commun
Prif Awduron: Sharma, Rajhans, KK, Sriram, Holmstrom, Erik D., Westerlund, Fredrik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577930/
https://ncbi.nlm.nih.gov/pubmed/32951838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.06.051
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