Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity

The antigenic and genomic stability of paramyxoviruses remains a mystery. Here, we evaluate the genetic plasticity of Sendai virus (SeV) and mumps virus (MuV), sialic acid-using paramyxoviruses that infect mammals from two Paramyxoviridae subfamilies (Orthoparamyxovirinae and Rubulavirinae). We perf...

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Publicat a:PLoS Pathog
Autors principals: Ikegame, Satoshi, Beaty, Shannon M., Stevens, Christian, Won, Taylor, Park, Arnold, Sachs, David, Hong, Patrick, Lee, Benhur, Thibault, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577504/
https://ncbi.nlm.nih.gov/pubmed/33035269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008877
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