Genome-Wide Transposon Mutagenesis in Pathogenic Leptospira Species

Leptospira interrogans is the most common cause of leptospirosis in humans and animals. Genetic analysis of L. interrogans has been severely hindered by a lack of tools for genetic manipulation. Recently we developed the mariner-based transposon Himar1 to generate the first defined mutants in L. int...

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Autors principals: Murray, Gerald L., Morel, Viviane, Cerqueira, Gustavo M., Croda, Julio, Srikram, Amporn, Henry, Rebekah, Ko, Albert I., Dellagostin, Odir A., Bulach, Dieter M., Sermswan, Rasana W., Adler, Ben, Picardeau, Mathieu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Bacterial Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632054/
https://ncbi.nlm.nih.gov/pubmed/19047402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01293-08
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