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Novel Antibiotics May Be Noninferior but Are They Becoming Less Effective?: a Systematic Review
Novel antibiotics approved by noninferiority trials may become less effective over time in two scenarios: (i) the treatment effect in studies of novel antibiotics may be consistently worse than studies of older antibiotics; (ii) when a decreasingly effective control arm is used in a series of noninf...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577162/ https://ncbi.nlm.nih.gov/pubmed/32900680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01597-20 |
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