Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients

Mutations in the genes of the F(420) signaling pathway of Mycobacterium tuberculosis complex, including dnn, fgd1, fbiA, fbiB, fbiC, and fbiD, can lead to delamanid resistance. We searched for such mutations among 129 M. tuberculosis strains from Asia, South America, and Africa using whole-genome se...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Reichmuth, Martina L., Hömke, Rico, Zürcher, Kathrin, Sander, Peter, Avihingsanon, Anchalee, Collantes, Jimena, Loiseau, Chloé, Borrell, Sonia, Reinhard, Miriam, Wilkinson, Robert J., Yotebieng, Marcel, Fenner, Lukas, Böttger, Erik C., Gagneux, Sebastien, Egger, Matthias, Keller, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577131/
https://ncbi.nlm.nih.gov/pubmed/32868333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00513-20
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