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Dexmedetomidine Mediates Neuroglobin Up-Regulation and Alleviates the Hypoxia/Reoxygenation Injury by Inhibiting Neuronal Apoptosis in Developing Rats
BACKGROUND: Exploring the effective therapy for neonatal hypoxic-ischemic brain injury is an important goal. This study was designed to investigate how dexmedetomidine (DEX) contribute to hypoxic brain injury. METHODS: Developing Sprague-Dawley rat models of hypoxia/reoxygenation (H/R) injury were c...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577010/ https://ncbi.nlm.nih.gov/pubmed/33117159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.555532 |
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