Lycopene Protects against Hypoxia/Reoxygenation Injury by Alleviating ER Stress Induced Apoptosis in Neonatal Mouse Cardiomyocytes

Endoplasmic reticulum (ER) stress induced apoptosis plays a pivotal role in myocardial ischemia/reperfusion (I/R)-injury. Inhibiting ER stress is a major therapeutic target/strategy in treating cardiovascular diseases. Our previous studies revealed that lycopene exhibits great pharmacological potent...

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Pubblicato in:PLoS One
Autori principali: Xu, Jiqian, Hu, Houxiang, Chen, Bin, Yue, Rongchuan, Zhou, Zhou, Liu, Yin, Zhang, Shuang, Xu, Lei, Wang, Huan, Yu, Zhengping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546295/
https://ncbi.nlm.nih.gov/pubmed/26291709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136443
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