KPC1 alleviates hypoxia/reoxygenation‐induced apoptosis in rat cardiomyocyte cells though BAX degradation

Bax triggers cell apoptosis by permeabilizing the outer mitochondrial membrane, leading to membrane potential loss and cytochrome c release. However, it is unclear if proteasomal degradation of Bax is involved in the apoptotic process, especially in heart ischemia‐reperfusion (I/R)‐induced injury. I...

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Udgivet i:J Cell Physiol
Main Authors: Yuan, Ye, Wang, Yong‐yi, Liu, Xin, Luo, Bin, Zhang, Lei, Zheng, Fei, Li, Xing‐Yuan, Guo, Ling‐Yun, Wang, Lu, Jiang, Miao, Pan, Ya‐mu, Yan, Yu‐wen, Yang, Jian‐ye, Chen, Shi‐You, Wang, Jia‐Ning, Tang, Jun‐Ming
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771896/
https://ncbi.nlm.nih.gov/pubmed/31148189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28854
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