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An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1

BACKGROUND: Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be used to modulate processes such as replication, transcription, DNA repair and mai...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Patel, Manthan, Patel, Divyesh, Datta, Subhamoy, Singh, Umashankar
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576722/
https://ncbi.nlm.nih.gov/pubmed/33081720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07526-5
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