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CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity

Abstract Background The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF occupancy by CGGBP1 remains unknown. Results By ana...

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主要な著者: Manthan Patel, Divyesh Patel, Subhamoy Datta, Umashankar Singh
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2020-07-01
シリーズ:BMC Genetics
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オンライン・アクセス:http://link.springer.com/article/10.1186/s12863-020-00894-8
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