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CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity

BACKGROUND: The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF occupancy by CGGBP1 remains unknown. RESULTS: By analyzing...

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Vydáno v:BMC Genet
Hlavní autoři: Patel, Manthan, Patel, Divyesh, Datta, Subhamoy, Singh, Umashankar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392725/
https://ncbi.nlm.nih.gov/pubmed/32727353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00894-8
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