Mainstreaming germline BRCA1/2 testing in non-mucinous epithelial ovarian cancer in the North West of England

Poly(ADP-ribose) polymerase (PARP) inhibitors improve survival in BRCA-mutant high-grade serous ovarian carcinoma. As a result, germline and somatic BRCA1/2 testing has become standard practice in women diagnosed with ovarian cancer. We outline changes in testing and detection rates of germline BRCA...

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Publicado no:Eur J Hum Genet
Main Authors: Flaum, Nicola, Morgan, Robert D., Burghel, George J., Bulman, Michael, Clamp, Andrew R., Hasan, Jurjees, Mitchell, Claire L., Badea, Doina, Moon, Sarah, Hogg, Martin, Hadjiyiannakis, Dennis, Clancy, Tara, Schlecht, Helene, Woodward, Emma R., Crosbie, Emma J., Edmondson, Richard J., Wallace, Andrew J., Jayson, Gordon C., Lalloo, Fiona I., Harkness, Elaine F., Evans, D. Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575602/
https://ncbi.nlm.nih.gov/pubmed/32651552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-020-0692-y
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