Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis

TP53 is a critical tumor suppressor that is mutated in approximately 50% of human cancers. Unveiling the downstream target genes of TP53 that fulfill its tumor suppressor function is an area of intense investigation. Zmat3 (also known as Wig-1 or PAG608) is one such downstream target of p53, whose l...

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Publicado en:Cell Death Dis
Autores principales: Best, Sarah A., Vandenberg, Cassandra J., Abad, Etna, Whitehead, Lachlan, Guiu, Laia, Ding, Sheryl, Brennan, Margs S., Strasser, Andreas, Herold, Marco J., Sutherland, Kate D., Janic, Ana
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575595/
https://ncbi.nlm.nih.gov/pubmed/33082333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03066-9
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