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Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes
Studies on the amyloidogenic N-terminal domain of the E. coli HypF protein (HypF-N) have contributed significantly to a detailed understanding of the pathogenic mechanisms in neurodegenerative diseases characterised by the formation of misfolded oligomers, by proteins such as amyloid-β, α-synuclein...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7575562/ https://ncbi.nlm.nih.gov/pubmed/33082392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74841-z |
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