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Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes

Studies on the amyloidogenic N-terminal domain of the E. coli HypF protein (HypF-N) have contributed significantly to a detailed understanding of the pathogenic mechanisms in neurodegenerative diseases characterised by the formation of misfolded oligomers, by proteins such as amyloid-β, α-synuclein...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Farrugia, Maria Ylenia, Caruana, Mario, Ghio, Stephanie, Camilleri, Angelique, Farrugia, Claude, Cauchi, Ruben J., Cappelli, Sara, Chiti, Fabrizio, Vassallo, Neville
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575562/
https://ncbi.nlm.nih.gov/pubmed/33082392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74841-z
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