CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos

OBJECTIVES: DNA damage and errors of accurate chromosome segregation lead to aneuploidy and foetal defects. DNA repair and the spindle assembly checkpoint (SAC) are the mechanisms developed to protect from these defects. Checkpoint kinase 1 (CHK1) is reported to be an important DNA damage response p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Prolif
Egile Nagusiak: Ju, Jia‐Qian, Li, Xiao‐Han, Pan, Meng‐Hao, Xu, Yao, Sun, Ming‐Hong, Xu, Yi, Sun, Shao‐Chen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574881/
https://ncbi.nlm.nih.gov/pubmed/32914523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12895
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