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Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands

Highly enantioselective conjugate addition reactions of arylboronic acids to 2-substituted chromones catalyzed by palladium complexes with new chiral Pyridine-Dihydroisoquinoline (PyDHIQ) ligands have been developed. These reactions provide highly enantioselective access to chromanones containing te...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Baek, Doohyun, Ryu, Huijeong, Ryu, Ji Yeon, Lee, Junseong, Stoltz, Brian M., Hong, Sukwon
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574023/
https://ncbi.nlm.nih.gov/pubmed/33133484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00412j
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