Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin–Heat-Labile Toxin Chimera

Recent efforts to develop an enterotoxigenic Escherichia coli (ETEC) vaccine have focused on the antigenically conserved tip adhesins of colonization factors. We showed previously that intranasal immunization with dsc(19)CfaE, a soluble variant of the in cis donor strand-complemented tip adhesin of...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: O'Dowd, Aisling, Maciel, Milton, Poole, Steven T., Jobling, Michael G., Rollenhagen, Julianne E., Woods, Colleen M., Sincock, Stephanie A., McVeigh, Annette L., Gregory, Michael J., Maves, Ryan C., Prouty, Michael G., Holmes, Randall K., Savarino, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573451/
https://ncbi.nlm.nih.gov/pubmed/32839188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00252-20
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