Effect of Zebularine in Comparison to and in Combination with Trichostatin A on CIP/KIP Family (p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2), DNMTs (DNMT1, DNMT3a, and DNMT3b), Class I HDACs (HDACs 1, 2, 3) and Class II HDACs (HDACs 4, 5, 6) Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Colon Cancer LS 174T Cell Line

BACKGROUND: A pattern of epigenetic modifications and changes, DNA methylation and histone modification, is central to many human cancers. A variety of tumor suppressor genes (TSGs) have been demonstrated to be silenced because of histone deacetylation and DNA hypermethylation in several cancers. Re...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Asian Pac J Cancer Prev
Главные авторы: Sanaei, Masumeh, Kavoosi, Fraidoon
Формат: Artigo
Язык:Inglês
Опубликовано: West Asia Organization for Cancer Prevention 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573409/
https://ncbi.nlm.nih.gov/pubmed/32711442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2020.21.7.2131
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы