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Effect of vorinostat on INK4 family and HDACs 1, 2, and 3 in pancreatic cancer and hepatocellular carcinoma

BACKGROUND AND PURPOSE: In mammalian cells, several distinct surveillance systems, named cell cycle checkpoints, can interrupt normal cell-cycle progression. The cyclin-dependent kinases are negatively regulated by proteins of cyclin-dependent kinases inhibitors comprising INK4 and Cip/Kip families....

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Bibliographic Details
Published in:Res Pharm Sci
Main Authors: Sanaei, Masumeh, Kavoosi, Fraidoon
Format: Artigo
Language:Inglês
Published: Wolters Kluwer - Medknow 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216159/
https://ncbi.nlm.nih.gov/pubmed/34221059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.314824
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