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Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation

Among the multiple antiviral defense mechanisms found in prokaryotes, CRISPR-Cas systems stand out as the only known RNA-programmed pathways for detecting and destroying bacteriophages and plasmids. Class 1 CRISPR-Cas systems, the most widespread and diverse of these adaptive immune systems, use an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Tina Y., Doudna, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573268/
https://ncbi.nlm.nih.gov/pubmed/32817336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.007034
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