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Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
Type III-A CRISPR-Cas systems are prokaryotic RNA-guided adaptive immune systems that use a protein-RNA complex, Csm, for transcription-dependent immunity against foreign DNA. Csm can cleave RNA and single-stranded DNA (ssDNA), but whether it targets one or both nucleic acids during transcription el...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6611850/ https://ncbi.nlm.nih.gov/pubmed/31278272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10780-2 |
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