Blocking of efflux transporters in rats improves translational validation of brain radioligands

BACKGROUND: Positron emission tomography (PET) is a molecular imaging technique that can be used to investigate the in vivo pharmacology of drugs. Initial preclinical evaluation of PET tracers is often conducted in rodents due to the accessibility of disease models as well as economic considerations...

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Bibliografische gegevens
Gepubliceerd in:EJNMMI Res
Hoofdauteurs: Shalgunov, Vladimir, Xiong, Mengfei, L’Estrade, Elina T., Raval, Nakul R., Andersen, Ida V., Edgar, Fraser G., Speth, Nikolaj R., Baerentzen, Simone L., Hansen, Hanne D., Donovan, Lene L., Nasser, Arafat, Peitersen, Siv T., Kjaer, Andreas, Knudsen, Gitte M., Syvänen, Stina, Palner, Mikael, Herth, Matthias M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2020
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572968/
https://ncbi.nlm.nih.gov/pubmed/33074370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00718-x
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