Blocking of efflux transporters in rats improves translational validation of brain radioligands

BACKGROUND: Positron emission tomography (PET) is a molecular imaging technique that can be used to investigate the in vivo pharmacology of drugs. Initial preclinical evaluation of PET tracers is often conducted in rodents due to the accessibility of disease models as well as economic considerations...

詳細記述

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書誌詳細
出版年:EJNMMI Res
主要な著者: Shalgunov, Vladimir, Xiong, Mengfei, L’Estrade, Elina T., Raval, Nakul R., Andersen, Ida V., Edgar, Fraser G., Speth, Nikolaj R., Baerentzen, Simone L., Hansen, Hanne D., Donovan, Lene L., Nasser, Arafat, Peitersen, Siv T., Kjaer, Andreas, Knudsen, Gitte M., Syvänen, Stina, Palner, Mikael, Herth, Matthias M.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2020
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572968/
https://ncbi.nlm.nih.gov/pubmed/33074370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00718-x
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