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A Global Map of G Protein Signaling Regulation by RGS Proteins

The control over the extent and timing of G protein signaling is provided by the regulator of G protein signaling (RGS) proteins that deactivate G protein α subunits (Gα). Mammalian genomes encode 20 canonical RGS and 16 Gα genes with key roles in physiology and disease. To understand the principles...

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Bibliographic Details
Published in:Cell
Main Authors: Masuho, Ikuo, Balaji, Santhanam, Muntean, Brian S., Skamangas, Nickolas K., Chavali, Sreenivas, Tesmer, John J.G., Babu, M. Madan, Martemyanov, Kirill A.
Format: Artigo
Language:Inglês
Published: Cell Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572916/
https://ncbi.nlm.nih.gov/pubmed/33007266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.08.052
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