Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Triple-negative breast cancer (TNBC) and HER2-positive breast cancer are particularly aggressive and associated with unfavorable prognosis. TNBC lacks effective treatments. HER2-positive tumors have treatment options but often acquire resistance to HER2-targeted therapy after initial response. To ad...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncogene
मुख्य लेखकों: Doheny, Daniel, Sirkisoon, Sherona, Carpenter, Richard L., Aguayo, Noah Reeve, Regua, Angelina T., Anguelov, Marlyn, Manore, Sara G., Arrigo, Austin, Jalboush, Sara Abu, Wong, Grace L., Yu, Yang, Wagner, Calvin J., Chan, Michael, Ruiz, Jimmy, Thomas, Alexandra, Strowd, Roy, Lin, Jiayuh, Lo, Hui-Wen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572897/
https://ncbi.nlm.nih.gov/pubmed/32929154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01454-1
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