HLA Genotyping in Synovial Sarcoma: Identifying HLA-A*02 and its Association with Clinical Outcome

PURPOSE: To determine if a targeted exome panel utilizing matched normal DNA can accurately detect germline and somatic HLA genes in synovial sarcoma (SS) patients and whether select HLA-A*02 genotypes are prognostic or predictive of outcome in metastatic SS. EXPERIMENTAL DESIGN: Metastatic SS patie...

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Udgivet i:Clin Cancer Res
Main Authors: Rosenbaum, Evan, Seier, Kenneth, Bandlamudi, Chaitanya, Dickson, Mark, Gounder, Mrinal, Keohan, Mary L., Chi, Ping, Kelly, Ciara, Movva, Sujana, Nacev, Benjamin, Simeone, Noemi, Donoghue, Mark, Slotkin, Emily K., Qin, Li-Xuan, Antonescu, Christina R., Tap, William D., D’Angelo, Sandra P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572879/
https://ncbi.nlm.nih.gov/pubmed/32816945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0832
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