Clinical Outcome of Leiomyosarcomas With Somatic Alteration in Homologous Recombination Pathway Genes

PURPOSE: To detect alterations in DNA damage repair (DDR) genes, measure homologous recombination deficiency (HRD), and correlate these findings with clinical outcome in patients with leiomyosarcoma (LMS). PATIENTS AND METHODS: Patients with LMS treated at Memorial Sloan Kettering (MSK) Cancer Cente...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Rosenbaum, Evan, Jonsson, Philip, Seier, Kenneth, Qin, Li-Xuan, Chi, Ping, Dickson, Mark, Gounder, Mrinal, Kelly, Ciara, Keohan, Mary L., Nacev, Benjamin, Donoghue, Mark T. A., Chiang, Sarah, Singer, Samuel, Ladanyi, Marc, Antonescu, Cristina R., Hensley, Martee L., Movva, Sujana, D’Angelo, Sandra P., Tap, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2020
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713532/
https://ncbi.nlm.nih.gov/pubmed/33283135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.20.00122
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