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EZH2-mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells

The majority of women diagnosed with epithelial ovarian cancer (OC) eventually develop recurrence which rapidly evolves into chemoresistant disease. Persistence of ovarian cancer stem cells (OCSC) at the end of therapy may be responsible for emergence of resistant tumors. In this study, we demonstra...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Zong, Xingyue, Wang, Weini, Ozes, Ali, Fang, Fang, Sandusky, George E., Nephew, Kenneth P.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572866/
https://ncbi.nlm.nih.gov/pubmed/32816909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-0458
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