Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective

Influenza B virus (IBV) infections can cause severe disease in children and the elderly. Commonly used antivirals have lower clinical effectiveness against IBV compared to influenza A viruses (IAV). Neuraminidase (NA), the second major surface protein on the influenza virus, is emerging as a target...

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Pubblicato in:Immunity
Autori principali: Madsen, Anders, Dai, Ya-Nan, McMahon, Meagan, Schmitz, Aaron J., Turner, Jackson S., Tan, Jessica, Lei, Tingting, Alsoussi, Wafaa B., Strohmeier, Shirin, Amor, Mostafa, Mohammed, Bassem M., Mudd, Philip A., Simon, Viviana, Cox, Rebecca J., Fremont, Daved H., Krammer, Florian, Ellebedy, Ali H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572813/
https://ncbi.nlm.nih.gov/pubmed/32976769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.08.015
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