Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity

Apolipoprotein (APOE) e4 genotype is an accepted risk factor for accelerated cognitive aging and dementia, though its neurostructural substrates are unclear. The deleterious effects of this genotype on brain structure may increase in magnitude into older age. This study aimed to investigate in UK Bi...

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Detalhes bibliográficos
Publicado no:Brain Imaging Behav
Main Authors: Lyall, Donald M., Cox, Simon R., Lyall, Laura M., Celis-Morales, Carlos, Cullen, Breda, Mackay, Daniel F., Ward, Joey, Strawbridge, Rona J., McIntosh, Andrew M., Sattar, Naveed, Smith, Daniel J., Cavanagh, Jonathan, Deary, Ian J., Pell, Jill P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572345/
https://ncbi.nlm.nih.gov/pubmed/30903549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11682-019-00069-9
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