Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity

Apolipoprotein (APOE) e4 genotype is an accepted risk factor for accelerated cognitive aging and dementia, though its neurostructural substrates are unclear. The deleterious effects of this genotype on brain structure may increase in magnitude into older age. This study aimed to investigate in UK Bi...

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Bibliografiska uppgifter
I publikationen:Brain Imaging Behav
Huvudupphovsmän: Lyall, Donald M., Cox, Simon R., Lyall, Laura M., Celis-Morales, Carlos, Cullen, Breda, Mackay, Daniel F., Ward, Joey, Strawbridge, Rona J., McIntosh, Andrew M., Sattar, Naveed, Smith, Daniel J., Cavanagh, Jonathan, Deary, Ian J., Pell, Jill P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2019
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572345/
https://ncbi.nlm.nih.gov/pubmed/30903549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11682-019-00069-9
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